The Internist’s Guide to PJP

Host: Dr. Sheliza Halani
Invited Guest: Dr. Nisha Andany (Infectious Diseases)

Resources:

1. 1. Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV

   2. Roux A, Canet E, Valade S, et al. Pneumocystis jirovecii pneumonia in patients with or without AIDS, France. Emerg Infect Dis 2014;20:1490-7.

   3. Morris, A., & Norris, K. A. (2012). Colonization by Pneumocystis jirovecii and its role in disease. Clinical microbiology reviews, 25(2), 297–317.
   4. Jonathan E. Kaplan, Debra Hanson, Mark S. Dworkin, Toni Frederick, Jeanne Bertolli, Mary Lou Lindegren, Scott Holmberg, Jeffrey L. Jones, Epidemiology of Human Immunodeficiency Virus-Associated Opportunistic Infections in the United States in the Era of Highly Active Antiretroviral Therapy, Clinical Infectious Diseases, Volume 30, Issue Supplement_1, April 2000, Pages S5–S14
   5. Pneumocystis jirovecii pneumonia prophylaxis in a 42-year-old woman on immunosuppressive therapy. Sheliza Halani, Nisha Andany, Rupal Shah. CMAJ Oct 2020, 192 (43) E1306-E1308
   6. Montaner, J. S., Lawson, L. M., Levitt, N., Belzberg, A., Schechter, M. T., & Ruedy, J. (1990). Corticosteroids prevent early deterioration in patients with moderately severe Pneumocystis carinii pneumonia and the acquired immunodeficiency syndrome (AIDS). Annals of internal medicine, 113(1), 14–20.
   7. Hsu, J. M., Hass, A., Gingras, M. A., Chong, J., Costiniuk, C., Ezer, N., Fraser, R. S., McDonald, E. G., & Lee, T. C. (2020). Radiographic features in investigated for Pneumocystis jirovecii pneumonia: a nested case-control study. BMC infectious diseases, 20(1), 492.
   8. Ding, L., Huang, H., Wang, H., & He, H. (2020). Adjunctive corticosteroids may be associated with better outcome for non-HIV Pneumocystis pneumonia with respiratory failure: a systemic review and meta-analysis of observational studies. Annals of intensive care, 10(1), 34. https://doi.org/10.1186/s13613-020-00649-9
   9. No need for secondary Pneumocystis jirovecii pneumonia prophylaxis in adult people living with HIV from Europe on ART with suppressed viremia and a CD4 cell count great than 100 cells/µL